Pure Encapsu
SAMe (S-Adenosylmethionine) (60 Caps)
Provides 200 mg per capsule of SAMe in an enhanced stability form Made using a solvent-free manufacturing process Helps promote a healthy mood balance Helps relieve osteoarthritis pain Made with hypoallergenic and vegan ingredients SAMe (S-adenosylmethionine) is a metabolite found in all living cells. It functions as a methyl group donor in over 100 different reactions and aids in the synthesis, activation, and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids, and proteins. Methyl groups act as a signal throughout the body, regulating gene expression and cellular function. SAMe also promotes a healthy mood balance, as indicated by over 40 clinical studies. In a meta-analysis of 25 controlled trials and 791 people, SAMe offered statistically significant support for positive mood, believed to be due to its support for monoamine neurotransmitter synthesis and function, including dopamine and serotonin. It also promotes healthy protein turnover and maintains healthy phospholipid methylation to support phosphatidylcholine production and cell membrane integrity and fluidity. Studies suggest it also promotes joint flexibility and comfort in people with osteoarthritis. In a meta-analysis of 11 studies, SAMe offered statistically significant support for joint function. It is believed to relieve osteoarthritis pain by supporting proteoglycan synthesis, as well as helping to stabilize and protect proteoglycans.
